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Translocation of a gut pathobiont drives autoimmunity in mice and humans

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These reactions are not specific to the bacterial strains but can be triggered by any component of the capsule, including the inulin or inactive ingredients

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The Endocrine Society's 2020 position statement on peptide therapeutics emphasizes that "the absence of Phase I dose-escalation data for novel peptides like BPC-157 means that any dose recommendation is extrapolated, not validated, and clinicians should err on the side of the lowest effective dose" 19