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However, melanoma of the lip, although rare, can sometimes look similar to a melanotic macule in its early stages, which is why dermatologists recommend that any new pigmented lesion on the lip, or any existing one that changes in size, color, or shape, should be evaluated to rule out a more serious diagnosis

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[8] They found no acute toxicity at doses up to 10 mg/kg

Potential Research Applications: Melanogenesis and skin pigmentation studies UV protection and tanning research models Libido and sexual function investigations Energy regulation and melanocortin receptor research For laboratory research only

SODs found in human are divided into cytosolic CuZn-SOD (SOD1), mitochondrial Mn-SOD (SOD2), and extracellular (SOD3) SOD enzymes