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AOD9604 and hGH significantly upregulated 3-AR expression in the WAT of ob/ob mice, correlating with the observed reductions in adipose tissue mass

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Without it, cells become large and inefficient, leading to persistent exhaustion

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Treatment with 5-amino-1mq upregulates proliferationrelated genes (Ki67, PCNA), promotes cell cycle progression, and improves cell fusion efficiency to form more multinucleated myotubes, achieving functional levels similar to those of young mice.Additionally, 5-amino-1mq inhibits muscle stem cell apoptosis, reduces oxidative stress damage, and maintains stemness