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The peptide has not undergone the extensive clinical testing typically required for regulatory approval as a pharmaceutical treatment in the United States or European Union

Research and development for these drugs required decades of investment and billions in clinical trial spending before reaching market approval

Although they originated as diabetes medications, GLP-1 drugs like Wegovy (semaglutide) and Zepbound (tirzepatide) have proven to be highly effective for weight loss

Common Side Effects and How to Manage Them GLP-1 medications are generally well-tolerated when used under medical supervision, but side effects - particularly gastrointestinal effects - are common, especially during the early weeks and after dose increases

McGovern, L., et al