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However, no large-scale human clinical trials have been completed, so long-term safety data in humans remains limited

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It is resistant and stable in the human gastric juice (more than 24 h [42]), acting as a membrane stabilizer, counteracting leaky gut syndrome, as a particular target [19] distinctive from the standard peptide growth factors [16] (i.e., standard peptide growth factors are rapidly destroyed in human gastric juice [42]), with particular molecular pathways involved [15,19,20,28,43,44,45,46,47,48,49,50]

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