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The mRNA levels of the anti-oxidant genes ( Gpx4 , Gsr , Glrx , and Nqo1 ) decreased and those of the pro-oxidant genes ( Alox15 and Lpo ) increased in the testes of S8/ Gss / mice at 8 months of age (Fig

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Structural plasticity among glutathione transferase phi members: natural combination of catalytic residues confers dual biochemical activities

The researchers documented significantly lower frontal gray matter glutathione levels compared to healthy controls, directly linking this localized, severe oxidative stress to the clinical presentation of brain fog and memory loss

Foran SE, Flood JG, Lewandrowski KB