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Switching to a non-GLP-1 medication This transition requires the most caution

To minimize discomfort during dose adjustments, patients should be advised to: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or spicy foods that may exacerbate nausea Stay well-hydrated , particularly if experiencing vomiting or diarrhea Take the injection on the same day each week , ideally when they can rest if needed Avoid lying down immediately after eating to reduce reflux symptoms Timing considerations are important

Lillys orforglipron (Foundayo), FDA-approved April 2026, is oral but not tirzepatide: 11.2% loss at 72 weeks, no food or water restrictions

Is It Safe to Combine Tirzepatide and Testosterone

Show them how to use an EpiPen if you have one