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These individuals cannot efficiently convert cyanocobalamin to the active methylcobalamin form, which is required for methionine synthase activity in the methyl donor cycle

Clinical research progress In summary, the pathological features of MDD and pharmacological mechanism of antidepressants have been widely studied

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For most healthy adults, the clinical trials at common doses do not demonstrate clear, proven harms, but the TMAO question remains an area of active research

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