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Alterations in DNA methylation patterns induce the expression of oncogenes or silence the expression of tumor-suppressor genes

It reduces the expression of apoptotic signaling molecules by inhibiting them and increasing the expression of anti apoptotic signaling molecules Apoptosis of cells and promotion of their proliferation and repair

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Thus, it does appear to be reasonable to hypothesize that GABA might be involved in the appetite control via acting on its receptors in the gastrointestinal tract and brain, which in turn influences the secretion of gut hormones and activates central neurons, respectively

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