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However, it is also known that TMAO is also present in high concentration in seafood, which is associated with a positive (beneficial) cardiovascular effect

Strong evidence supporting use for corneal injuries and neurotrophic keratopathy once approved

Observational studies analyzed like randomized experiments: an application to postmenopausal hormone therapy and coronary heart disease

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In a cross-sectional study on 109 children with PWS aged 218 years (50 with obesity and 59 without obesity), and 96 controls with simple obesity matched for age, gender and BMI, it was shown that children with PWS without obesity showed significantly lower frequency of hypertension (12%) than subjects with PWS and obesity (32%), and controls with simple obesity (35%), suggesting the crucial role of obesity rather than the syndrome per se in the absence of excessive weight [37]