For instance, tirzepatide recently gained approval for treating moderate to severe obstructive sleep apnea in adults with obesity
Glucagon receptor activation can increase energy expenditure and may promote fat use, but it can also raise glucose in some contexts, which is why the balance of the three pathways matters
Improved glucose control, reduced visceral fat, better inflammatory signaling, and reduced cardiovascular risk all carry long-term health impact
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Ethics declarations Ethics approval All procedures, protocols, and medications were approved by the Johns Hopkins University Animal Care and Use Committee and were performed in accordance with the Association for Research in Vision and Ophthalmology statement for use of animals in ophthalmic and vision research, and the National Institutes of Health guide for the care and use of laboratory animals