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Thyroid function, insulin resistance, stress hormones, and sleep all shape how your metabolism responds, which is why we look at thyroid and adrenal health and broader hormone balance alongside the injection itself
What I found was that people who respond poorly to GLP-1 monotherapy often have a stronger glucagon-driven component to their metabolic dysfunction
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These findings support the use of liraglutide as an effective GLP-1 agent to add to metformin