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Parallel randomized studies in Hashimoto thyroiditis and Graves disease should pre-specify metabolic co-endpoints (Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and Magnetic Resonance Imaging-Proton Density Fat Fraction (MRI-PDFF) for liver fat) to test the immunometabolic hypothesis suggested by observational signals and secondary analyses [32,60]

The buddy benefit: increasing the effectiveness of an employee-targeted weight-loss program

Therefore, given the association with improved nutritional status under semaglutide treatment, this GLP-1RA could be explored in other obesity-related conditions, including fatty liver disease, dyslipidemia, hypertension, and potentially even cancer

Ugwoaba UA et al

Pierce Logan is a Graduate Assistant at the Indiana University Center for Bioethics.