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Our data suggest that choline can promote liver health by maintaining cholesterol homeostasis.10 Choline induces glucose and insulin intolerance in Pemt(-/-) mice through modulating plasma glucagon and its action in liver.11 Choline supplementation decreased the concentration of liver triacylglycerol during the first 4 wk after parturition

In cases of diagnostic uncertainty, additional tests such as holotranscobalamin or methylmalonic acid may be considered

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11 Hydroxocobalamin injections are often recommended for those with B12 deficiency as it is retained in the blood for longer and binds more firmly to the TC II transport protein than other forms of B12

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