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Fat tissue plays an active role in oestrogen production, so a rapid reduction in body fat can lower circulating oestrogen levels, disrupting the hormonal signals that regulate the menstrual cycle

In June 2021 the FDA approved Semaglutide for chronic weight management in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes or high cholesterol)

Journey Cards give you a way to celebrate consistency, not just a big drop on the scale

However, this was predominantly driven by one trial, DECLARE TIMI 58, which included healthier cohorts than other cardiovascular outcome trials (CVOT) involving SGLT-2 inhibitors [103], and this benefit of asthma risk reduction was neutralized when DECLARE TIMI 58 was excluded from the analysis [105]