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Also, a higher yolk pigmentation has been related to the reduction of oxidative stress in the GIT and with higher absorption of carotenoid pigments (Galamatis et al

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This significantly elevates Angiotensin II (Ang II) levels, a key RAAS mediator, which induces intestinal epithelial injury through four main pathways: (1) Ang II selectively inhibits P-glycoprotein (Pgp) function and membrane expression in intestinal epithelial cells via AT1 receptor-mediated PI3K/Akt-p38 MAPK signaling