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Study participants who had obesity, HFpEF, and diabetes who received semaglutide lost more than double the weight of participants on placebo, were able to walk farther during a timed test, and saw a drop in heart failure and inflammation-related biomarkers, according to the trial published in The New England Journal of Medicine , which included more than 600 participants

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Good News Overall, using a GLP-1 compared to another diabetes drug was associated with a whole slew of beneficial outcomes

Besides, the GLP-1R/GGCR dual agonist, Cotadutide, was shown to relieve steatosis, inflammation and fibrosis in both Ob/Ob NASH mice model and C57BI/6J NASH mice model (131)

Many users also take it to support skin appearance, such as dullness and uneven-looking tone, alongside sun protection and good nutrition