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Some phenotypes plausibly need a slower-than-label climb: lighter bodies (higher exposure per milligram), a history of severe GLP-1 gut intolerance, a high baseline heart rate, or a lean, low-reserve build

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Mautes A.E., Weinzierl M.R., Donovan F., Noble L.J

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10 Conclusion This review systematically analyzes the mechanisms, clinical evidence, and research gaps underlying how nutrients improve depression by regulating gut microbiota