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In addition to established endocrine mechanisms, such as glucose-dependent insulin secretion, delayed gastric emptying, and appetite suppression, GLP-1 RAs engage in complex bidirectional interactions with the intestinal ecosystem (58)
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Median duration of use was 5 years, with only four cases reported with courses 3 months or shorter and eight cases reported with use 1 year or less
Para pacientes con insuficiencia cardaca o enfermedad renal crnica, los inhibidores SGLT2 son generalmente preferidos, aunque los GLP-1 pueden ser una alternativa o complemento valioso
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