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Description

Patients with cirrhosis often show elevated endogenous GH but reduced IGF-1 because hepatocytes cannot respond normally to GH receptor signaling

J Thorac Cardiovasc Surg 158(5):1475-1478, 2019

These immunological alterations which have characterized our current understanding of Covid-19 suggest that agents which target immune modulation, rather than direct viricidal activity, may present exciting targets for pharmacological intervention