In Parkinsons, GSH deficiency is one of the earliest biochemical manifestations of the disease, leading to oxidative stress and nerve damage
Conversion between bound- and free-form glutathione releases and receives hydrogen atom and thiol compounds, respectively, which may induce physiological responses
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The standard dosage for severe deficiency typically starts with 1 mg daily injections, transitioning to weekly and then monthly maintenance doses
Additionally, its formulation exhibited good antioxidant activity, as well as a proliferative effect and adequate biocompatibility