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Higher peptide concentrations (above 2mg/mL) increase aggregation risk and reduce solution stability, making larger vial sizes with dilute mixes preferable for extended protocols
identified neural precursor cell-expressed developmentally downregulated protein 4 (NEDD4)-mediated GPX4 ubiquitination as a central driver of HG-induced ferroptosis in CCSMCs, exacerbating DMED through oxidative stress, Ras homolog gene family member A (RhoA)/Rho-associated coiled-coil-containing kinase (ROCK) activation, and fibrosis [62]
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