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Evidence Evidence that CFS/ME patients are low in methylation cycle metabolites: B vitamin evidence In a small study of 58 chronic fatigue syndrome patients with a history of Epstein-Barr infection and B-cell immunodeficiency, 81% responded to folinic acid

If you have complex health concerns, consult with your healthcare professional

Vitamin B12 supports red blood cell production, neurological function, and energy metabolism

Excessive nitric oxide production represents another theoretical concern

IL-1, a principal initiator of gouty inflammation, works together with multiple chemokines to guide neutrophils toward sites of MSU crystal deposition