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Early data are promising: retatrutide, a leading candidate in this class, produced 24.2% average weight loss at 48 weeks in a Phase 2 trial, exceeding results seen with current medications

5.8% (OR 0.57, 95% CI 0.291.09, p = 0.084)

Heres whats important to know: the warning is based on rare cases of medullary thyroid carcinoma found in animal studies

Participants taking the highest dose experienced glycated hemoglobin (HbA1c) reductions of approximately 2.0 percentage points, alongside weight loss in the range of 1617% at 36 weeks again outperforming comparator agents in cross-trial context

The pricing was the first honest thing I'd seen in this whole space one number, no add-ons