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Metabonomic alterations in hippocampus, temporal and prefrontal cortex with age in rats

Weight loss alone does not fully capture the biochemical adaptations occurring during prolonged GLP-1RA therapy, particularly those related to substrate redistribution, redox balance, and micronutrient-dependent metabolic processes

The substance is poorly characterized

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It also underscores why the result should not be read as a general fat-burning effect: the trials measured a specific fat compartment in a specific population, using CT imaging, not overall body weight or cosmetic slimming