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Semaglutide, a long-acting GLP-1 agonist, exhibited a sustained weight decrease of approximately 15% of body weight in clinical studies, whereas tirzepatide, a combination GIP/GLP-1 agonist, attained a weight loss of up to 22.5% in the SURMOUNT trials [36,37]

Intrauterine devices (IUDs), subdermal implants, and hormone injections deliver contraception through non-oral routes, eliminating the interaction risk

Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD + /SIRT3 pathway

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10.1016/j.cell.2023.01.040