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134 In a trial in 109 men with infertility, 350 mg DHA three times daily for 90 days improved sperm motility, viability, and morphology and decreased sperm DNA fragmentation compared with placebo

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Therapies that do not cause any change in the host genome include the use of non-coding RNA (nc-RNA) antisense oligonucleotides (ASO), RNA editing, and gene delivery