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Targeting piRNA-137463 inhibits tumor progression and boosts sensitivity to immune checkpoint blockade via De Novo cholesterol biosynthesis in lung adenocarcinoma

127 Invasion and metastasis The invasion-metastasis cascade is the defining phenotype of tumor cell proliferation and is recognized as the most lethal aspect of tumor progression

It decreases body weight, as a result of increasing in glutathione production

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GGT is localized to the cell surface and cleaves only extracellular substrates, GSH, and oxidized GSH (GSSG), its most abundant ones