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They work through completely different receptor systems and metabolic pathways

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Ozempic (semaglutide) is a prescription GLP-1 receptor agonist that suppresses appetite, slows stomach emptying, and regulates blood sugar

In addition, nicotinamide, the primary NNMT substrate 95,96 , is broken down by Lactobacillus arabinosis into nicotinic acid and ammonia 56

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