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10.1007/s00394-017-1445-8 151

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A proprietary analysis of each companys Orange Book listings using the Federal Circuits new standard would identify the magnitude of the vulnerability more precisely

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Endothelial cells modulate BBB integrity via junction proteins, vascular cell adhesion molecule-1, intercellular adhesion molecule-1, chemokine receptor, Calcium/calmodulin-dependent protein kinase kinase and , adenosine receptor 2a, the C3a/C3a receptor signaling pathway, and the fibroblast growth factor receptor 1/Kelch-like ECH-associating protein 1 (Keap1)/NF-E2 related factor-2 (Nrf2) activation pathway

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