Thats not because they failed. Its because hunger signaling often returns when the medication is removed, and the body tends to defend its prior weight
Participants who took a placebo and received the same lifestyle interventions lost only 3 per cent of their body weight
For Weight Loss (Saxenda) Approved for adults with: BMI 30 (obesity) BMI 27 (overweight) + weight-related conditions (e } Liraglutide vs Other GLP-1 Agonists Liraglutide was one of the first GLP-1 drugs, but now there are newer options like semaglutide ( Wegovy , Ozempic )
To be effective, your knee OA treatment protocol should include weight management, dietary modifications, lifestyle interventions, knee stabilizer strengthening, and pain management strategies that do not involve drugs or steroids
In chronic conditions like diabetes and obesity, where standard dosing may not be effective for all patients, off-label prescribing is common