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doi: 10.1177/193229681100500633 53

What research does confirm about Aloe is that its a great moisturizer and has several anti-inflammatory (among others contains salicylates, polysaccharides, magnesium lactate and C-glucosyl chromone) as well as some antibacterial components

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Patients considering or taking GLP-1 medications should understand that whilst these drugs offer proven benefits for diabetes and weight management, any effects on acne are likely indirect and related to the metabolic and hormonal changes that accompany weight loss and improved insulin sensitivity, rather than a specific therapeutic action on acne itself

Effect of melatonin and epithalon on age-related disturbances in hormonal functions of the female reproductive system in monkeys