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CL is particularly useful for imaging antioxidant distribution in tissues and evaluating oxidative stress in diseases such as rheumatoid arthritis and Parkinsons disease (Hughes et al., 2018), while fluorescence provides superior spatial and temporal resolution, making it preferred for cellular imaging applications (Prolo et al., 2018)

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However Lillys demonstration that a GIP/GLP-1 receptor co-agonist (tirzepatide) has superior efficacy compared to selective GLP-1 receptor agonists, has renewed interest in the first incretin. Lilly rolled out their SURPASS trials to position their agent amongst existing diabetes medications and GLP-1 agonists