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Avoid sugary drinks, and be mindful that caffeine may worsen gastrointestinal symptoms in some individuals

This issue could not be addressed by CADTH reanalysis due to the lack of available comparative clinical evidence for use in combination with treatments other than metformin with or without a sulfonylurea, or as monotherapy in patients intolerant to metformin

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This could potentially affect how well the drug works or lead to a spike in side effects