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It is well established that elevated extracellular adenosine reduces seizure activity in several seizure models, and the anticonvulsant action is mediated through A 1 R adenosine receptors (104, 105)

The titration period: To minimize digestive side effects, doctors typically start with a low dose and gradually increase it over several months

26 Rhabdomyomas protrude into the cardiac chambers in 50%, 27 a characteristic observed more often in patients who do not have tuberous sclerosis

ISO-administered rats also exhibited higher nitric oxide levels, which were associated with increased NO generation and iNOS expression during the acute phase of MI 41

(Clinical trial evaluating an oral non-peptide GLP-1 receptor agonist)