Neurochem Res 40:25272543 Higgins RD, Raju T, Edwards AD, Azzopardi DV, Bose CL, Clark RH, Ferriero DM, Guillet R, Gunn AJ, Hagberg H, Hirtz D, Inder TE, Jacobs SE, Jenkins D, Juul S, Laptook AR, Lucey JF, Maze M, Palmer C, Papile L, Pfister RH, Robertson NJ, Rutherford M, Shankaran S, Silverstein FS, Soll RF, Thoresen M, Walsh WF (2011) Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop
Malaguarnera, M., Gargante, M
Researchers became interested in combining these peptides when early studies revealed their complementary pharmacokinetics: Ipamorelin peptide provides an immediate GH pulse (peaking within 40 minutes), while CJC-1295 sustains release over several hours
Access this article Similar content being viewed by others Abbreviations ALCAR: Acetyl-l-carnitine OCTN2: Organic cation transporter novel 2 CPT I: Carnitine palmitoyltransferase I CPT II: Carnitine palmitoyltransferase II CAT: Carnitine acetyltransferase MRS: Magnetic resonance spectroscopy 13 C-NMR: 13 C-nuclear magnetic resonance spectroscopy OGD: Oxygen-glucose deprivation HI: Hypoxia-ischemia TBI: Traumatic brain injury 3-NPA: 3-nitropropionic acid i.p.: Intraperitoneal CSF: Cerebrospinal fluid mTOR: Mammalian target of rapamycin NGF: Nerve growth factor pNFH: Phosphorylated high-molecular weight neurofilament rCMRglc: Cerebral regional metabolic rate of glucose TBI: Traumatic brain injury TCA: Tricarboxylic acid References Jones LL, McDonald DA, Borum PR (2010) Acylcarnitines: role in brain
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