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Rearing was defined as a mouse standing up on its hind limbs while leaning on the wall with one or both paws (supported rearing) or without wall support (unsupported rearing)

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Protective effect of caffeic acid on cardiac markers and lipid peroxide metabolism in cardiotoxic rats: an in vivo and in vitro study

A decrease in IGF-1 leads to reduced activity of the protein kinase B (AKT)/mTOR pathway, which in turn activates FOXO1 (21, 192)