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1c, d) 57,58

Consider all the toxins (free radicals, pesticides, cleaning products, radiation, or heavy metals, for example) that your body comes into contact with daily, in addition to the normal daily stress

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it is a qualitative difference in how they influence energy balance, appetite, and organ function

Now imagine this effect on tens (if not hundreds) of millions of people as these drugs get more effective, the clinical indications expand, and treatment regimens become less frequent