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202.3 A tree-based graded response theory model to test for differential item functioning in patient-reported outcome measures Olayinka Arimoro 1 , Matthew James 1 , Maria Santana 1 , Lisa Lix 2 , Tolulope Sajobi 1 1 University of Calgary, Calgary, Alberta, Canada, 2 University of Manitoba, Winnipeg, Manitoba, Canada Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :202.3 Aims Item-response theory models based on recursive partitioning have been developed for evaluating differential item functioning (DIF) in patient-reported outcome measures and for identifying population subgroups that exhibit DIF

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During the early years of perimenopause, symptoms may appear sporadically, with irregular cycles being the most obvious change

HPLC can help separate peptide-related components and support purity review through chromatographic data [12]