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In addition, DHA modulates key neuronal signaling pathways by influencing protein kinase C activity and synaptic protein assembly, thereby supporting neurotransmission, synaptic plasticity, and cognitive processes such as memory and learning

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extrapolation to the TB-500 fragment alone remains incomplete in the published literature

Based on the ternary complex model, Asp41 and His174 are specifically placed to interact with the ribose moieties of the FAD and NADH nucleotides, respectively (Fig