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The renewal of the gastric epithelium is ensured by stem cells located within the tubular glands 48 , where a subpopulation of fundic chief cells, expressing Lgr5, has been identified and can function as injury-responsive reserve stem cells 49

Works Through a Different Mechanism Because PT-141 works differently from PDE5 inhibitors, it may benefit people whose dysfunction is not primarily vascular

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Human leukocyte antigen alleles encode histocompatibility glycoproteins that enable the initiation of a specific immune response through the presentation of antigens to T cells and have been identified as risk factors for other skin diseases such as psoriasis [34]