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GLP-1 1(2.5mg) 7,000 7,700 1(5.0mg) 12,000 13,200 GLP-1 GLP-1 GLP-1 GLP-1 GLP- GLP-1 01. GLP-1 02. 03. GLP-1 GLP-1 BMI 3 2GIPGLP-1-1GIPGLP-1 2GIPGLP-1GLP-1 1 12.5mg2.5mg45mg15 mg4 GLP-197FDAGLP-11 11 0.611.2mg11.8mg 1.8mg GLP-1 GLP-1 111 1() 3~4 0.25mg40.5mg 40.5mg1.0mg 34 GLP-1 11 GLP-1 GLP-1 GLP-1 Q 1 A 1 Q A GLP-112122 Q A Q A 40 Q A GLP-12 92(BMI)27 Q A GLP-112122 Q A GLP-111 Q 1 A GLP-11180.630 Q A GLP-1 Q A FDA GLP-1

The mechanism of action is fundamentally different, targeting incretin receptors in the pancreas, brain, and gut rather than the kidneys

3.1.2 Prebiotics and probiotics Oral prebiotics or probiotics reduce the production of metabolites by changing the composition of the gut microbiota

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In the study of Queval et al