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Differential induction of extracellular glutathione peroxidase and nitric oxide synthase 2 in airways of healthy individuals exposed to 100% O(2) or cigarette smoke

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High levels (over 15 micromol/L) and low levels (below 5 micromol/L) are affected by factors like diet, exercise, medications, age, sex, and health

Although Cys can be generated via the transsulfuration pathway in some cell types, in many other cell types, at least in vitro , the import of cystine via system is significant for maintaining the levels of Cys and GSH, and preventing ferroptosis (Magtanong and Dixon, 2018)

In vitro and in vivo assays will be conducted to investigate the impact of kisspeptin-10 on GnRH release and subsequent gonadotropin secretion