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For example, GLP-1 enhances L-type Ca 2+ currents through activation of the cAMP-dependent PKA pathway in canine cardiomyocytes [71], whereas when rat hippocampal neurons are pre-incubated with GLP-1 for 24 h, Ca 2+ currents are significantly decreased [58]

Detoxification: In the liver, glutathione conjugates with toxins, making them more water-soluble and easier to excrete through urine or bile