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Wegovy is also approved to reduce the risk of serious cardiovascular events, such as heart attack and stroke, in adults with cardiovascular disease and obesity or overweight

In the present experiments, antagonising either the glucagon or GLP-1 receptor reduced or completely abolished the effect of glucagon on somatostatin secretion, suggesting that both receptors are involved in glucagons regulation of the delta cell

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Loss of meal-induced decrease in plasma ghrelin levels in patients with anorexia nervosa

In 2026, results from a larger and longer phase 3 trial supported these findings