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Although the VPA model effectively recapitulates key ASD phenotypes, future work must validate these findings in genetic subtypes (e.g., Shank3 KO) and decipher causal microbiota-neuroimmune crosstalk via fecal transplantation

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Regarding tolerability and post treatment side effects in two groups, only one patient in the first group developed mild erythema on right side, which subsided within few hours without any treatment

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