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Neurotransmitters systems Serotonin Serotonin has a widespread neuromodulatory role in cortical and sub-cortical functional pathways implicated in mood, cognition and sleep, all of which are affected in aging, LLD and neurodegenerative disease [53]

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Mean NADP+ ( A ) and NADPH ( B ) levels in A549shNRF2-BIND-luc cells treated with water (Control) or 2.5 ng/mL doxycycline (Dox) for 48 h