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10.1016/j.juro.2006.10.065 40 GressnerA

Two people have actually died from severe electrolyte imbalances due to using coffee enemas

Moreover, birefringent deposits highly suggestive of monosodium urate crystals have been detected in the coronary arteries, as well as prostate, and tophi can develop in cardiac valves

Another study in healthy individuals did not observe statistically significant changes in hsCRP or TNF one day after a psilocybin dose

Now, that doesn't mean that the risk ever goes to zero for any of us, regardless of ApoE genotype, but I know that if I have to choose between being very-insulin-sensitive and not-so-insulin-sensitive I'm going to be better off in this camp