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Nakanishi, 1992, Ozawa and Rossier, 1996)

placebo: 55% vs

Bonds are formed as a result of the interaction between atoms and molecular structure is formed due to these bonds

Furthermore, a similar results were reported in a study of individuals with or without oligozoospermic which showed no significant association between DNA methylation in spermatozoa and the MTHFR C677T genotypes although a trend for higher incidence of methylation alterations in severe oligozoospermic infertile men with CT genotypes were observed 34 , suggesting that a much more complicated or indirect interactions between MTHFR polymorphism and methylation are involved

Another important issue is the risk of falsely positive associations due to multiple comparisons in regression analysis