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Single-cell RNA sequencing (scRNA-seq) has revealed the cellular heterogeneity within ovarian follicles and endometrial tissue, while spatial transcriptomics has provided insights into tissue architecture and cell-cell communications [7,8,9,10]

As patients lose weightsometimes substantiallythe musculoskeletal system must adapt to altered biomechanics and reduced load-bearing

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For example, if a patient has been taking a maintenance dose of Ozempic at 1 mg or 2 mg weekly, they will often begin Mounjaro at 2.5 mg weekly

For long-term use, some providers reduce patients to a lower maintenance dose after reaching their weight goal